Manufacturing News / YMC America, Inc.

New Brochure Describes YMC-SEC MAB HPLC Column Optimized for Large Protein Sizing Separations

Via: ReleaseWire

Updated 11:14 AM CST, Mon, February 25,2019

Allentown, PA -- (SBWIRE) -- 02/25/2019 -- In a new 2 page flyer, YMC America describes its new size exclusion column optimized for aggregates and fragments of monoclonal antibodies (mAb).

YMC-SEC MAB is a size exclusion chromatography (SEC) column that utilizes a dihydroxypropyl stationary phase bonded to a 3 µm silica gel base with 250Å pore size.

3µm particle size delivers high resolution, and the 250Å pore size makes YMC-SEC MAB an excellent choice for separating mAb aggregates from monomer, as well as effectively resolving lower molecular weight fragments.

YMC-SEC MAB exhibits excellent resolution and peak shape over a wide molecular weight range of 10kDa to 700kDa.

YMC-SEC MAB is also useful for SEC analysis of antibody drug conjugates using organic-containing mobile phases.

A column durability test shown in the flyer illustrates no meaningful change of theoretical plate number and elution time after more than 500 injections when used for monoclonal antibody analysis.

The flyer also documents lot-to-lot reproducibility of the columns and shows separations of humanized monoclonal antibody (mAb) and antibody-drug conjugate (ADC). These columns exhibit high reproducibility lot-to-lot, coupled with long useful lifetime, making them ideal for both research and quality control applications.

Read more about YMC-SEC MAB at: https://www.ymcamerica.com/ymc-sec-mab/.

For a copy of the YMC-SEC MAB flyer, contact: info@ymcamerica.com; call 888-341-8380.

About YMC America, Inc.
Established in 1980, YMC America, Inc. is worldwide full-service liquid chromatography company, which offers sales, technical product support, service, application assistance, purification services, contract synthesis and method development.

All YMC products are available worldwide through YMC's network of subsidiaries. This worldwide presence as a full-range chromatography supplier ensures that all YMC products are fully available and fully supported both locally and globally.

See: https://www.ymcamerica.com/

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