Manufacturing News / YMC America, Inc.

New Brochure Describes YMC-Triart Bio C4 HPLC Column for Biomolecule Separations

Via: ReleaseWire

Updated 10:06 AM CST, Mon, February 11,2019

Allentown, PA -- (SBWIRE) -- 02/11/2019 -- In a new 2 page flyer, YMC America describes its reversed phase stationary phase for analyzing intact monoclonal antibodies (mAb), proteins, and oligonucleotides. Reversed phase separation can be a useful alternative to SEC or IEX.

YMC-Triart BIO C4 is based on a hybrid-silica particle which is stable at elevated temperatures. Access to the use of elevated temperature enables the elution of some mAbs, such as Bevacizumab, which remain adsorbed on-column at and below 50°C.

YMC-Triart BIO C4 has a pore size of 300Å, making it ideal for use with large molecule analysis. For high efficiency in reversed-phase mode, Triart BIO C4 is available in 5 µm, 3 µm, and even 1.9 µm for UHPLC.

YMC-Triart BIO C4 was developed specifically for HPLC and UHPLC separations of intact antibodies and other large proteins. This hybrid-silica based butyl phase is especially effective when used for intact antibody analysis at high temperatures and is ideal for high-sensitivity analysis using mass spec-friendly mobile phases.

Triart Bio C4 Highlights
Organic/Inorganic Hybrid-Silica Particle
C4 (USP L26) Stationary Phase
Available in 1.9µm (for UHPLC), 3µm, and 5µm Particle Sizes
300Å Pore Size – ideal for mAbs and other large proteins
Polymeric Bonding – for added ruggedness and reliability
Proprietary Endcapping – provides excellent peak shape

In the Flyer
The flyer includes all Triart BIO C4 specs, as well as examples of chromatograms of Bevacizumab, and other various proteins. Complete Triart BIO C4 ordering information is also provided.

Download the Triart BIO C4 flyer at:

For more information, visit or call 888-341-8380.

About YMC America, Inc.
Established in 1980, YMC America, Inc. is worldwide full-service liquid chromatography company, which offers sales, technical product support, service, application assistance, purification services, contract synthesis and method development.

All YMC products are available worldwide through YMC's network of subsidiaries. This worldwide presence as a full-range chromatography supplier ensures that all YMC products are fully available and fully supported both locally and globally.


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